

The Zhao Lab
Stephenson School of Biomedical Engineering
University of Oklahoma, Norman campus
Complete list of publications in Google Scholar
Journal Publications
[23] Chuan Li, Quan Le, Julian O. Kimura, Bingying Zhao, Yunzhe Li, Jian Zhao, Thomas Bifano, Brandon Weissbourd, John T. Ngo, and Jerome Mertz, “Superresolution imaging of live samples by centroid reassignment microscopy” Preprint, bioRxiv, doi: https://doi.org/10.1101/2025.08.03.668310 (2025).
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[22] Haonan Zong, Celalettin Yurdakul, Jian Zhao, Zian Wang, Fukai Chen, M. Selim Ünlü, and Ji-Xin Cheng, “Bond-Selective Full-Field Optical Coherence Tomography” Optics Express, 31 pp.41202-41218 (2023).
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[21] Jian Zhao (Co-corresponding author), Lulu Jiang, Alex Matlock, Yihong Xu, Jiabei Zhu, Hongbo Zhu, Lei Tian, Benjamin Wolozin, and Ji-Xin Cheng, “Mid-infrared Chemical Imaging of Intracellular Tau Fibrils using Fluorescence-guided Computational Photothermal Microscopy” Light: Science & Applications, 12, Article number: 147 (2023).
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[20] Xiaowen Hu, Jian Zhao (Corresponding author), Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, and Axel Schülzgen, “Unsupervised Full-color Subcellular Image Reconstruction through Anderson Localizing Optical Fiber” Light: Science & Applications, 12, Article number: 125 (2023).
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[19] Xiaowen Hu, Jian Zhao (Corresponding author), Jose E. Antonio-Lopez, Stefan Gausmann, Rodrigo Amezcua Correa, and Axel Schülzgen, “Adaptive Inverse Mapping: A Model-free Semi-supervised Learning Approach towards Robust Imaging through Dynamic Scattering Media” Optics Express, 31, pp.14343 (2023).
[18] Jian Zhao, Alex Matlock, Hongbo Zhu, Ziqi Song, Jiabei Zhu, Biao Wang, Fukai Chen, Yuewei Zhan, Zhicong Chen, Yihong Xu, Xingchen Lin, Lei Tian, Ji-Xin Cheng, “Bond-Selective Intensity Diffraction Tomography,” Nature Communications, 13, Article number: 7767 (2022).
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[17] Stefan Gausmann, Xiaowen Hu, Jian Zhao, MD. Selim Habib, He Cheng, Jose Enrique Antonio-Lopez, Xiaoming Yu, Rodrigo Amezcua Correa, and Axel Schülzgen, “Tuneable Dispersion and Supercontinuum Generation in Disordered Glass-air Anderson Localization Fiber,” Journal of Lightwave Technology, 41, pp. 2484-2493 (2022).
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[16] (Invited)Jian Zhao (corresponding author) and Mingsheng Li, “Lensless ultrafast optical imaging,” Light: Science & Applications, 11: 97 (2022).
[15] Jian Zhao (corresponding author), Xiaowen Hu, Stefan Gausmann, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, and Axel Schülzgen, “Learning-Based Image Transport Through Disordered Optical Fibers With Transverse Anderson Localization,” Frontiers in Physics 9:593, DOI: 10.3389/fphy.2021.710351 (2021).
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[14] Lulu Jiang, et al., Jian Zhao, Ji-Xin Cheng, Leonard Petrucelli, Hu Li, Andrew Emili, Benjamin Wolozin, “Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy,” Molecular Cell, 81, 4209–4227.e12, (2021)
[13] Ryan M. Hekman, et al., Jian Zhao, et al., Ji-Xin Cheng, Benjamin L. Wolozin, et al., Andrew A. Wilson, Andrew Emili, and Elke Mühlberger, “Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2,” Molecular Cell, 80, pp.1104-1122.e9 (2020).
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[12] Xiaowen Hu, Jian Zhao (corresponding author), Jose E. Antonio-Lopez, Shengli Fan, Rodrigo Amezcua Correa, and Axel Schülzgen, “Robust Imaging-free Object Recognition through Anderson Localizing Optical Fiber,” Journal of Lightwave Technology, 39, pp. 920-926 (2020).
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[11] Lulu Jiang, Jian Zhao (co-first author), Jixin Cheng, and Benjamin Wolozi, “Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins,” Frontiers in Neurology, 11:579434. doi: 10.3389/fneur.2020.579434 (2020).
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[10] Jing Zhang, Jian Zhao (co-first author), Haonan Lin, Yuying Tan, and Jixin Cheng, “High-Speed Chemical Imaging by Dense-Net Learning of Femtosecond Stimulated Raman Scattering,” Journal of Physical Chemistry Letters, 11, 8573–8578 (2020).
[9] Jian Zhao (corresponding author), Yangyang Sun, Hongbo Zhu, Zheyuan Zhu, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Deep Learning Cell Imaging through Anderson Localizing Optical Fiber,” Advanced Photonics, 1(6), 066001 (2019).
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[8] Jian Zhao (corresponding author), Mostafa Peysokhan, Jose Enrique Antonio-Lopez, Yangyang Sun, Behnam Abaie, Arash Mafi, Rodrigo Amezcua-Correa, Shuo Pang, and Axel Schülzgen, “A Path to High-Quality Imaging through Disordered Optical Fibers: A Review,” Applied Optics 58(13), D50-D60 (2019).
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[7] Hongbo Zhu, Shengli Fan, Jian Zhao, Xingchen Lin*, Li Qin, and Yongqiang Ning, “Development and Thermal Management of kW-Class High-Power Diode Laser Source Based on the Structure of Two-Stage Combination,” IEEE Photonics Journal 11(3), 1502510 (2019).
[6] Jian Zhao (corresponding author), Yangyang Sun, Zheyuan Zhu, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Deep Learning Imaging through Fully-Flexible Glass-Air Disordered Fiber,” ACS Photonics 5(10), 3930-3935 (2018).
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[5] Jian Zhao (corresponding author), et al., Rodrigo Amezcua Correa, and Axel Schülzgen, “Image Transport Through Meter-Long Randomly Disordered Silica-Air Optical Fiber,” Scientific Reports 8(1) : 3065 (2018).
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[4] Behnam Abaie, Mostafa Peysokhan, Jian Zhao, Jose E. Antonio-Lopez, Rodrigo Amezcua-Correa, Axel Schülzgen, and Arash Mafi*, “Disorder-induced high-quality wavefront in an Anderson localizing optical fiber,” Optica 5(8), 984-987 (2018).
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[3] Shengli Fan, Seth Smith-Dryden, Jian Zhao, Stefan Gausmann, Axel Schülzgen, Guifang Li*, and Bahaa E.A. Saleh*, “Optical Fiber Refractive Index Profiling by Iterative Optical Diffraction Tomography,” Journal of Lightwave Technology 36, 5754-5763 (2018).
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[2] Yang Wang, Tianyi Guo, Jialin Li, Jian Zhao, et al., Zenghu Chang*, et al., Daniel M Neumark, and Stephen R Leone, “Enhanced High-order Harmonic Generation Driven by A Wavefront Corrected High-energy Laser,” Journal of Physics B: Atomic, Molecular and Optical Physics 51(13), 134005 (2018).
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[1] Donghui Zheng, Lei Chen*, Jinpeng Li, Qinyuan Sun, Wenhua Zhu, James Anderson, Jian Zhao, Axel Schülzgen, “Circular carrier squeezing interferometry: Suppressing Phase Shift Error in Simultaneous Phase-shifting Point-diffraction Interferometer,” Optics and Lasers in Engineering 102,136-142 (2018).
Conference Publications
[16] Xiaowen Hu, Jian Zhao*, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, and Axel Schülzgen, “Imaging through Disordered Optical Fiber System Using Unsupervised Learning,” Conference on Lasers and Electro-Optics (CLEO) 2022, paper STu5P.4.
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[15] Xiaowen Hu, Jian Zhao*, Jose Enrique Antonio-Lopez, Youyou Cheng, Rodrigo Amezcua Correa, and Axel Schülzgen, “Stabilized Depth Cell Imaging through Disordered Fiber System with Semi-supervised Learning Algorithm,” Conference on Lasers and Electro-Optics (CLEO) 2021, paper FM3L.4.
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[14] Xiaowen Hu, Jian Zhao*, Shengli Fan, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, and Axel Schülzgen, "Learning-Supported Full-Color Cell Imaging Through Disordered Optical Fiber," Conference on Lasers and Electro-Optics (CLEO) 2020, paper SM2L.5.
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[13] Jing Zhang, Haonan Lin, Jian Zhao, Yuying Tan, and Jixin Cheng*, “High-Speed Multiplexed Vibrational Imaging by Femtosecond Stimulated Raman Scattering and Deep Learning,” Conference on Lasers and Electro-Optics (CLEO) 2020, paper AW3T.3.
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[12] (Invited) Jian Zhao*, Shengli Fan, Jose Enrique Antonio-Lopez, and Axel Schülzgen, “Deep Learning Imaging through Specialty Multi-mode Fibers,” Optical Fiber Communication Conference (OFC) 2020, paper W1B.1.
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[11] Paul Roth*, Gordon K. L. Wong, Jian Zhao, Jose Enrique Antonio-Lopez, Rodrigo Amezcua-Correa, Michael H. Frosz, Philip St. J. Russell, Axel Schülzgen, “Wavelength dependence of transverse Anderson localization in disordered glass-air fiber,” Sixth International Workshop on Specialty Optical Fibers and Their Applications — WSOF 2019, Proc. of SPIE 11206 1M-1.
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[10] Jian Zhao*, Yangyang Sun, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, Axel Schülzgen, “Cell Imaging Using Glass-Air Disordered Optical Fiber and Deep Learning Algorithms,” Imaging and Applied Optics 2019 (COSI, IS, MATH, pcAOP), Computational Optical Sensing and Imaging 2019, paper CW1A.2.
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[9] Jian Zhao*, Yangyang Sun, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Robust Cell Imaging through Anderson Localizing Optical Fiber Based on Deep Learning,” Conference on Lasers and Electro-Optics (CLEO) 2019, paper STh3L.2.
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[8] Jian Zhao*, Yangyang Sun, Zheyuan Zhu, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Randomly Disordered Glass-Air Optical Fiber Imaging Based on Deep Learning,” Advanced Photonics 2018 (BGPP, IPR, NP, NOMA, Sensors, Networks, SPPCom, SOF), Specialty Optical Fibers 2018, paper SoW1H.2.
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[7] Jian Zhao*, Yangyang Sun, Zheyuan Zhu, Donghui Zheng, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Bending-Independent Imaging through Glass-Air Disordered Fiber Based on Deep Learning,” Imaging and Applied Optics 2018 (3D, AO, AIO, COSI, DH, IS, LACSEA, LS&C, MATH, pcAOP), Computational Optical Sensing and Imaging 2018, paper CW3B.6.
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[6] Jian Zhao*, Yangyang Sun, Zheyuan Zhu, Donghui Zheng, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Shuo Pang, and Axel Schülzgen, “Deep-Learning-Based Imaging through Glass-Air Disordered Fiber with Transverse Anderson Localization,” Conference on Lasers and Electro-Optics (CLEO) 2018, paper STu3K.3.
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[5] Behnam Abaie, Mostafa Peysokhan, Jian Zhao, Jose E. Antonio-Lopez, Rodrigo Amezcua-Correa, Axel Schlzgen, and Arash Mafi*, “Nearly diffraction limited beam qualities in an Anderson localizing optical fiber,” Conference on Lasers and Electro-Optics (CLEO) 2018, paper STu3K.2.
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[4] J. E. Antonio-Lopez*, Jian Zhao, J. C. Alvarado-Zacarias, Joel Villatoro, Axel Schülzgen, and Rodrigo Amezcua Correa, “Dual-core fiber interferometer for sensing applications,” Fifth Workshop on Specialty Optical Fibers and Their Applications — WSOF 2017, Proc. of SPIE Vol. 10604 1060401-176.
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[3] (Invited) Jian Zhao*, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Donghui Zheng, and Axel Schülzgen, “Image Transport Through Meter-Long Silica-Air Disordered Optical Fiber,” Fifth Workshop on Specialty Optical Fibers and Their Applications — WSOF 2017, Proc. of SPIE Vol. 10604 1060401-28.
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[2] Jian Zhao*, Jose Enrique Antonio-Lopez, Rodrigo Amezcua Correa, Arash Mafi, Marie Windeck, and Axel Schülzgen, “Image transport through silica-air random core optical fiber,” Conference on Lasers and Electro-Optics (CLEO) 2017, paper JTu5A.91.
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[1] Viktor O. Smolski, Sergey D. Gorelov, Jian Zhao, Jia Xu, Peter G. Schunemann, and Konstantin L. Vodopyanov*, “Frequency comb spanning 2.5-7.5 µm from a subharmonic GaAs OPO and its coherence properties,” Conference on Lasers and Electro-Optics (CLEO) 2015, paper STh1N.5.
Conference Presentations
[14](invited) “3D imaging of intracellular tau fibrils and jellyfish neuroscience models via computational chemical and fluorescence microscopy,” SPIE Photonics West 2025, Neural Imaging and Sensing PC1330304
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[13](invited) “High-speed computational multiphoton imaging through scattering media,” SPIE Photonics West 2024, Multiphoton Microscopy in the Biomedical Sciences XXIV, paper 12847-12
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[12](invited) “Unsupervised Learning-Based Optical Fiber Bio-Imaging,” Lab-on-a-Fiber Incubator: Technologies, Applications, and Opportunities 2023 Optica Global Headquarters
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[11] “Volumetric bond-selective imaging and spectroscopic analysis of cellular Tau fibrils through a fluorescence-guided computational chemical microscope,” SPIE Photonics West 2023, Advanced Chemical Microscopy for Life Science and Translational Medicine, paper 12392-3.
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[10] “Bond-selective full-field optical coherence tomography,” SPIE Photonics West 2023, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, paper 12367-51.
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[9] “Bond-selective intensity diffraction tomography,” SPIE Optics+Photonics, Enhanced Spectroscopies and Nanoimaging 2022, paper 12203-29.
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[8] “Bond-selective intensity diffraction tomography,” SPIE Photonics West, SPIE BiOS 2022, paper 11973-24.
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[7] “Stabilized imaging through dynamic scattering media based on generative adversarial networks,” SPIE Photonics West, SPIE BiOS 2022, paper 11974-19.
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[6] (invited)“Bond-selective Intensity Diffraction Tomography,” 2021 New England Society for Microscopy (NESM) Fall Symposium.
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[5] “Deep learning for high-quality imaging and accurate classification of cells through Anderson localizing optical fiber,” SPIE OPTO 2021, Proceedings Volume 11703, AI and Optical Data Sciences II; 117030Q (2021).
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[4] “Deep-Learning-Based Fiber Optic Imaging System,” Arizona Photonics Days 2021.
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[3] “Optical diffraction tomography with deep-field match optimization,” SPIE BiOS 2020, Proceedings Volume 11249, Quantitative Phase Imaging VI; 112490E.
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[2] (Invited)“Fully-flexible glass-air disordered fiber imaging through deep learning,” SPIE Defense + Commercial Sensing 2019, Computational Imaging IV, Paper 10990-12.
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[1] “Enhancement of wavefront characteristics in fibers by Anderson localized modes,” SPIE OPTO (SPIE, 2019), Vol. 10935.
